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Madagascar periwinkle, rosy periwinkle

Habit Subshrubs or herbs perennial, 3–10(–20) dm.
Leaves

petiole (1–)3–11 mm, sparsely pubescent or glabrous;

blade elliptic to obovate, oblong, or rarely lanceolate, (1–)2.5–9 × (0.6–)0.8–4 cm, membranous, base cuneate to attenuate, apex rounded to acute or obtuse, mucronulate, surfaces sparsely pubescent or glabrous.

Peduncles

1–4 mm, sparsely pubescent or glabrous, occasionally absent.

Pedicels

0–1 mm, sparsely pubescent or glabrous.

Flowers

calyx lobes narrowly lanceolate, 2–6 mm, sparsely pubescent or glabrous;

corolla eglandular-pubescent abaxially and adaxially, tube (15–)20–30 × 1–1.5 mm, throat 4–5 × 2–3 mm, lobes spreading, broadly obovate, often mucronulate, (5–)10–28 × 10–25 mm.

Seeds

1–3 × 0.5–1.5 mm.

Follicles

(12–)20–50 × 1.5–2 mm.

2n

= 16.

Catharanthus roseus

Phenology Flowering spring–fall; fruiting summer–fall.
Habitat Dis­turbed areas, old homesites.
Elevation 0–300 m. (0–1000 ft.)
Distribution
from FNA
AL; CA; FL; GA; KS; LA; MS; NC; SC; TN; TX; Indian Ocean Islands (Madagascar) [Introduced in North America]
[WildflowerSearch map]
[BONAP county map]
Discussion

Catharanthus roseus is of great pharmaceutical interest for its ability to synthesize a large number (ca. 130) of monoterpenoid indole alkaloids, the best known of which are vinblastine and vincristine (Q. Pan et al. 2016). When purified, both compounds have been shown to be useful for treating certain cancers, especially Hodgkin’s disease, non-Hodgkin’s lymphomas, and acute leukemia (R. Van der Heijden et al. 2004), and act by disrupting microtubules, causing dissolution of the mitotic spindle and metaphase arrest in dividing cells.

(Discussion copyrighted by Flora of North America; reprinted with permission.)

Source FNA vol. 14.
Parent taxa Apocynaceae > Catharanthus
Synonyms Vinca rosea, Lochnera rosea
Name authority (Linnaeus) G. Don: Gen. Hist. 4: 95. (1837)
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